In drugs, deep vein thrombosis (also called deep venous thrombosis and often abbreviated as DVT) is the formation of a blood clot ("thrombus") in a deep vein. It's a type of thrombophlebitis (inflammation of a vein with clot formation).

Deep vein thrombosis generally affects the leg veins (such as the femoral vein or the popliteal vein) or the deep veins of the pelvis. Sometimes the veins of the arm are affected (if spontaneous, this is known as Paget-Schrötter disease). A DVT can occur without symptoms, however in lots of cases the affected extremity shall be painful, swollen, red, heat and the superficial veins may be engorged. Essentially the most critical complication of a DVT is that the clot may dislodge and journey to the lungs, which is called a pulmonary embolism (PE). DVT is a medical emergency. All limb swellings nevertheless trivial, should be thought to be a DVT until confirmed otherwise. Untreated decrease extremity DVT has a 3% PE-associated mortality rate. Deaths associated with higher extremity DVT are extraordinarily rare. A late complication of DVT is the put up-thrombotic syndrome, which might present itself as edema, pain or discomfort and pores and skin problems.

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